Profil Klinis Pasien Meningoensefalitis di Instalasi Rawat Intensif RSUP. Dr. Kariadi Semarang
Keywords:clinical manifestations, laboratory examination, CT scans, meningoencephalitis
Introduction: Meningoencephalitis is an inflammation of the brain and brain membranes. The onset of the disease varies depending on the etiology. Meningoencephalitis causes fever, headaches, meningitis, changes in mental status, and/or seizures. Meningoencephalitis is diagnosed on an individual basis, with laboratory and imaging tests to back it up. Objective: The study's goal was to determine the clinical profile of adult meningoencephalitis patients admitted to Semarang's Dr. Kariadi Hospital's Intensive Care Unit. Method: The clinical profile includes clinical manifestations, laboratory examination results, and imaging. Results and discussion: There were 8 adult meningoencephalitis patients; women were more than men (63%); age groups that had the same high incidence (25%) were 17-25 years, 26-35 years, and 36-45 years; all patients presented with decreased consciousness (GCS ≤13); the most common clinical manifestations of meningoencephalitis are headache (100%), neck stiffness (87.5%), lateralization (75%), fever (62.5%); most of the patients (62%) had a lumbar puncture, with clear/colorless results (100%), high protein levels (80%), decreased glucose levels (60%), PMN cell pleocytosis (60%), MN cell pleocytosis ( 20%), there was no pleocytosis (20%); 75% of patients had a CT scan of the head, with half the imaging results supporting the picture of infection (50%). Conclusions: Meningoencephalitis patients mostly are women and young adults. Unconsciousness, headache were clinical manifestations that all patients experienced. The CSF examination results showed that bacteria became the first etiology. A Head CT scan did not always show an appearance of infection.
White JL, Sheth KN. Neurocritical Care for the Advanced Practice Clinician [Internet]. Springer International Publishing; 2017. Available from: https://books.google.co.id/books?id=6DIyDwAAQBAJ.
Huldani H. Diagnosis dan Penatalaksanaan Meningitis Tuberkulosis [Internet]. Banjarmasin: Fakultas Kedokteran; 2012 [cited 2021 Apr 9]. Available from: http://eprints.ulm.ac.id/206/.
Thapa LJ, Twayana RS, Shilpakar R, Ghimire MR, Shrestha A, Sapkota S, Rana PVS. Clinical profile and outcome of acute encephalitis syndrome (AES) patients treated in College of MedicalSciences-Teaching Hospital. Journal of College of Medical Sciences-Nepal. 2013;9(2):31-37.
Japardi I. Meningitis Meningococcus. 2002 May 23 [cited 2021 Apr 9]; Available from: https://repository.usu.ac.id/handle/123456789/1956.
Bartt R. Acute Bacterial and Viral Meningitis: CONTINUUM: Lifelong Learning in Neurology. 2012;18(6):1255–70.
Redenbaugh V, Flanagan EP. Understanding the etiology and epidemiology of meningitis and encephalitis: now and into the future. The Lancet Regional Health - Western Pacific. 2022;20:100380.
Wall EC, Cartwright K, Scarborough M, Ajdukiewicz KM, Goodson P, Mwambene J, et al. High Mortality amongst Adolescents and Adults with Bacterial Meningitis in Sub-Saharan Africa: An Analysis of 715 Cases from Malawi. PLOS ONE. 2013;8(7):e69783.
Encephalitis Society. Management of viral encephalitis guidelines | The Encephalitis
Society [Internet]. [cited 2021 Apr 9]. Available from: https://www.encephalitis.info/management-of-viral-encephalitis-guidelines.
Griffiths MJ, McGill F, Solomon T. Management of acute meningitis. Clin Med (Lond). 2018 Apr;18(2):164–9.
Masson E. Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines [Internet]. EM-Consulte. [cited 2022 Apr 9]. Available from: https://www.em-consulte.com/article/707401/management-of-suspected-viral-encephalitis-in-chil.
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