Hubungan Hipertensi Terhadap Kematian Pasien Covid-19 Dengan Diabetes Melitus Tipe 2 di RSUP dr. Sardjito

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Farah Fadhilah
Vina Yanti Susanti
Dhite Bayu Nugroho
Imam Manggalya Adhikara
Fitri Handajani


Diabetes mellitus and hypertension are co-morbidities that are often found in COVID-19 patients. Diabetes can reduce the body's immunity and increase the rate of viral replication, and is associated with vascular problems. Hypertension is one of the comorbid diabetes with high morbidity and mortality. To determine the relationship between hypertension and the death of COVID-19 patients with type 2 diabetes mellitus at Dr Sardjito General Hospital. Observational study with a retrospective cohort study design, using COVID-19 registry data at Dr Sardjito General Hospital for the period March 2020-July 2021. COVID-19 patients with type 2 diabetes mellitus who had hypertension and those who did not have hypertension were selected at Dr Sardjito General Hospital and Collected data on mortality, age, sex, other comorbidities, severity and length of stay. Data were processed using SPSS, in univariate, bivariate, and multivariate analysis models. the results of multivariate analysis using logistic regression found that hypertension, age, and ischemic heart disease did not have a significant association with the death of COVID-19 patients with type 2 diabetes mellitus. The variable that had the greatest power as a predictor of death in COVID-19 patients with diabetes mellitus type 2 is ARDS with a risk of death 20.8 times higher than without ARDS. Patients with kidney failure are at risk of dying 2.7 times higher than those without kidney failure. The addition of length of stay (LOS) 1 day of treatment reduces the risk of death by 16.3%. Hypertension has no significant relationship as a predictor of death in COVID-19 patients with type 2 diabetes mellitus at Dr Sardjito General Hospital. Significant predictors of death in this study were ARDS, kidney failure, and were associated with length of stay (LOS).



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Fadhilah, F. ., Susanti, V. Y. ., Nugroho, D. B. ., Adhikara, I. M. ., & Handajani, F. . (2024). Hubungan Hipertensi Terhadap Kematian Pasien Covid-19 Dengan Diabetes Melitus Tipe 2 di RSUP dr. Sardjito. CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal, 4(3).
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WHO, "WHO Director-General's opening remarks at the media briefing on COVID-19 - 11 March 2020," 2020. [Online]. Available: [Accessed 30 September 2022].

Satgas Penanganan COVID-19, "Data sebaran perkembangan Covid-19 di Indonesia," 2022. [Online]. Available: [Accessed 30 September 2022].

E. W. Wulandari, S. Ronoatmodjo and N. Salama, "Hubungan Komorbid Hipertensi dengan Kematian pada Kasus Konfirmasi COVID-19 di DKI Jakarta, Maret-Agustus 2020," Jurnal Ilmu Kesehatan Masyarakat, vol. 10, no. 4, pp. 287-298, 2021.

S. Sen, R. Chakraborty, P. Kalita and M. P. Pathak, "Diabetes mellitus and COVID-19: Understanding the association in light of current evidence," WJCC: World Journal of Clinical Cases, vol. 9, no. 28, pp. 8327-8339, 2021.

Z. Zhang, L. Zhang, D. Zha, C. Hu and X. Wu, "Clinical characteristics and risks of Chinàs 2019 novel coronavirus patients with AKI: a systematic review and meta-analysis.," Ren Fail, vol. 42, no. 1, pp. 926-931, 2020.

M. Akbariqomi, M. S. Hosseini, J. Rashidiani, H. Sedighian, H. Biganeh, R. Heidari, M. M. Moghaddam, G. Farnoosh and H. Kooshki, "Clinical characteristics and outcome of hospitalized COVID-19 patients with diabetes: A single-center, retrospective study in Iran," Diabetes Res Clin Pract, vol. 169, no. 108467, 2020.

M. Zakerkish, M. S. Fooladi, H. B. Shahbazian, F. Ahmadi, P. Payami S and D.-M. M., "Assessment of Mortality Rate, Need for ICU Admission and Ventilation in COVID-19 Patients with Diabetes Mellitus," Qatar Med J, vol. 1, no. 9, 2022.

A. Z. Fatoni and R. Rakhmatullah, "Acute Respiratory Distress Syndrome (ARDS) pada Pneumonia COVID-19," Journal of Anaesthesia and Pain, vol. 2, no. 1, pp. 11-24, 2021.

S. A. Bradley, M. Banach, N. Alvarado, I. Smokovski and S. M. M. Bhaskar, "Prevalence and impact of diabetes in hospitalized COVID-19 patients: A systematic review and meta-analysis," Journal of Diabetes, vol. 14, no. 2, pp. 144-157, 2021.

I. Huang, M. A. Lim and R. Pranata, "Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia – A systematic review, meta-analysis, and meta-regression," Diabetes Metabolic Syndrome, vol. 14, no. 4, pp. 395-403, 2020.

S. J. Tzotzos, B. Fischer, H. Fischer and M. Zeitlinger, "Incidence of ARDS and outcomes in hospitalized patients with COVID-19: a global literature survey," Crit Care, vol. 24, no. 1, 2020 .

X. Zhang, J. Yu, Y. Pan. L and H. Y. Jiang, "ACEI/ARB use and risk of infection or severity or mortality of COVID-19: A systematic review and meta-analysis," Pharmacological Research, vol. 158, no. 104927, 2020.

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