Psychological Stress and Seborrheic Dermatitis Outcomes: Insights from a Clinical Cohort in Southeast Asia
Main Article Content
Abstract
Seborrheic Dermatitis (DS) is a chronic skin disease that often occurs in areas rich in sebaceous glands, characterized by erythematous patches, plaques, and scales. Psychological factors, especially stress, will affect sebum production and colonization of Malassezia spp being the main cause of seborrheic dermatitis. Stress can increase skin inflammation and worsen DS symptoms. The severity of DS was assessed by the Seborrheic Dermatitis Area Severity Index (SDASI), while stress was measured by the Perceived Stress Scale (PSS). PSS is designed to measure the level of stress in everyday life. SDASI scale used to assess the severity of seborrheic dermatitis. The purpose of the study was to analyze the relationship between the level of stress measured using the Perceived Stress Scale (PSS) with the severity of seborrheic dermatitis evaluated through the Seborrheic Dermatitis Area Severity Index (SDASI). The study involved 51 patients who met the inclusion and exclusion criteria. Data collection was conducted through PSS questionnaires totaling 14 questions and SDASI assessment to measure the severity of DS. The results showed that most patients experienced very severe stress (88.2%) and the severity of severe SDASI (74.5%). The correlation between PSS and SDASI showed a p value of 0.010 (p < 0.05), which showed significant results between the level of stress with the severity of DS with correlation efficiency of 0.359..Stress can worsen the condition of seborrheic dermatitis in which an increase in PSS values is obtained.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
References
Del Giudice M, Buck CL, Chaby LE, Gormally BM, Taff CC, Thawley CJ, et al. What Is Stress? A Systems Perspective. Integr Comp Biol. 2018 Dec 1;58(6):1019–32.
Kim HY. Statistical notes for clinical researchers: Sample size calculation 1. comparison of two independent sample means. Restor Dent Endod. 2016;41(1):74.
Cömert A, Bekiroglu N, ¨ Urbüzurb¨urbüz OG, Ulin Ergun T¨. Efficacy of Oral Fluconazole in the Treatment of Seborrheic Dermatitis A Placebo-Controlled Study. Vol. 8, Am J Clin Dermatol. 2007.
Cömert A, Akbaş B, Kılıç EZ, Akın Ö, Gökçe E, Göktuna Z, et al. Psychiatric comorbidities and alexithymia in patients with seborrheic dermatitis: A questionnaire study in Turkey. Am J Clin Dermatol. 2013;14(4):335–42.
Kose O, Erbil H, Gur AR. Oral itraconazole for the treatment of seborrhoeic dermatitis: An open, noncomparative trial. Journal of the European Academy of Dermatology and Venereology. 2005 Mar;19(2):172–5.
Ghodsi SZ, Abbas Z, Abedeni R. Efficacy of Oral Itraconazole in the Treatment and Relapse Prevention of Moderate to Severe Seborrheic Dermatitis: A Randomized, Placebo-Controlled Trial. Am J Clin Dermatol. 2015 Oct 26;16(5):431–7.
İslamoğlu ZGK. Second-to-fourth digit ratio and seborrheic dermatitis in males: A cross-sectional study. An Bras Dermatol. 2019 May 1;94(3):327–30.
Lesage FX, Berjot S, Deschamps F. Psychometric properties of the french versions of the perceived stress scale. Int J Occup Med Environ Health. 2012;25(2):178–84.
Andreou E, Alexopoulos EC, Lionis C, Varvogli L, Gnardellis C, Chrousos GP, et al. Perceived Stress Scale: Reliability and validity study in Greece. Int J Environ Res Public Health. 2011 Aug 11;8(8):3287–98.
Lee EH. Review of the psychometric evidence of the perceived stress scale. Vol. 6, Asian Nursing Research. 2012. p. 121–7.
Jackson JM, Alexis A, Zirwas M, Taylor S. Unmet needs for patients with seborrheic dermatitis. Vol. 90, Journal of the American Academy of Dermatology. Elsevier Inc.; 2024. p. 597–604.
Choe SJ, Kim D, Kim EJ, Ahn JS, Choi EJ, Son ED, et al. Psychological Stress Deteriorates Skin Barrier Function by Activating 11β-Hydroxysteroid Dehydrogenase 1 and the HPA Axis. Sci Rep. 2018 Dec 1;8(1).
Gül Aİ, Karaaslan Ö, Çölgeçen E. Personality traits and common psychiatric conditions in patients with seborrheic dermatitis. Rev Psiquiatr Clín. 2017 Jan 1;44(1):6–9.
Bin Saif GA, Alotaibi HM, Alzolibani AA, Almodihesh NA, Albraidi HF, Alotaibi NM, et al. Association of psychological stress with skin symptoms among medical students. Saudi Med J. 2018 Jan 1;39(1):59–66.
Rao A, Douglas SC, Hall JM. Endocrine disrupting chemicals, hormone receptors, and acne vulgaris: A connecting hypothesis. Vol. 10, Cells. MDPI; 2021.
Urban K, Chu S, Giesey RL, Mehrmal S, Uppal P, Delost ME, et al. Burden of skin disease and associated socioeconomic status in Asia: A cross-sectional analysis from the Global Burden of Disease Study 1990-2017. JAAD Int. 2021 Mar 1;2:40–50.
Eldy, Hari Darmawan. Stress Levels and Seborrheic Dermatitis in the Class of 2020 Medical Students at a University in Indonesia. Folia Medica Indonesiana. 2023 Jun 10;59(2):115–22.